WELCOME TO THE

Dana-Farber Cancer Institute Center for Cancer Evolution

The Center for Cancer Evolution (CCE) was founded in 2016 by Dr. Franziska Michor at the Dana-Farber Cancer Institute.

The CCE is dedicated to understanding and steering tumor evolution. Our work encompasses evolutionary biology, clinical oncology, computational modeling and machine learning approaches to uncover the mechanisms driving cancer progression, metastasis, and therapeutic resistance. We develop and apply a broad spectrum of quantitative approaches to predict treatment outcomes and guide precision therapies. By integrating these tools with genomic, pharmacologic, and longitudinal clinical data, we aim to design patient-specific strategies that improve outcomes across diverse cancer types.

Email

cce@jimmy.harvard.edu

Office

Dana-Farber Cancer Institute
Attn: Christina Noonan, CLSB 11007
450 Brookline Avenue, Boston, MA 02215

News

Early dynamics of clinical and laboratory parameters predict primary refractory disease in patients with metastatic urothelial carcinoma receiving atezolizumab.

Graser C, McDonald TO, Catalano PJ, Sonpavde G, Michor F

Published in Journal for ImmunoTherapy of Cancer: May 7, 2025